There’s Android Translation Layer (ATL) which is currently being developed.

Not sure if it will meet your specs but I do hope it can replace Waydroid in the future.

I love Flatpaks. It’s always the default for me and I use Arch. Packages from the Arch repos or the AUR are almost always the last resort.

EndeavorOS is not automatic but you can set it up with one terminal command.

The only thing preventing Graphene from being adopted by Normie’s is the installation.

After that, it’s pretty much just Android.